Hüseyin Cumhur Tekin, PhD
Hüseyin Cumhur Tekin, PhD
İzmir Yüksek Teknoloji Enstitüsü, Biyomühendislik Bölümü
Fen Fakültesi A Blok, Oda 204
Gülbahçe Mahallesi, Urla/İzmir
PhD in Microsystems and Microelectronics, Ecole Polytechnique Federale de Lausanne (EPFL), Switzerland
Specialized in biomedical microfluidic systems
Thesis tittle: “Automated analysis of rare biomarkers using a magnetic bead surface coverage assay coupled with chaotic mixing on a microfluidic chip”
MSc in Electrical and Electronics Engineering, EPFL, Switzerland
Specialized in microelectronics and microfabrication
Thesis title: “Process optimization for resonators with lateral MOSET detection”
BSc in Electrical and Electronics Engineering, Middle East Technical University (METU), Turkey
Specialized in computer and telecommunication fields
Assistant Professor in Department of Bioengineering, Izmir Institute of Technology (IZTECH), Turkey
Founder and CEO of Saniber Software, Engineering, R&D and Healthcare Services Co., Turkey
Postdoctoral Research Fellow in Canary Center at Stanford for Cancer Early Detection, Department of Radiology, School of Medicine, Stanford University, USA
− Developed and characterized novel magnetic levitation based technology for real-time interrogation of both prokaryotic and eukaryotic cell types; enabled single-cell density measurements within a few minutes using automated program; used this technology for identification of cells and monitoring of heterogeneous biological changes under various physiological conditions, such as antibiotic or cancer treatment.
− Fabricated microfluidic chips composed of polymer micropillar arrays to sort efficiently motile sperms to be used in assisted reproductive technologies.
− Assisted in the development of graphene-based biosensors for early-detection of cancer by quantifying microRNA circulating in a blood stream based on electrical impedance spectroscopy.
Postdoctoral Research Fellow in Department of Bioengineering, Brigham and Women’s Hospital, Harvard- Massachusetts Institute of Technology (MIT) Division of Health Sciences and Technology, Harvard Medical School, USA
− Developed and optimized telemedicine platform for early detection of infections in dialysis patients by monitoring white blood cell counts in peritoneal dialysis effluents.
− Collaborated with Brazilian scientists from Fiocruz (Belo Horizonte), IBMP (Curitiba) and CERTI (Florianopolis) to detect schitosoma eggs from stool samples in rural fields of Brazil using a microfluidic chip coupled with a lensless imaging system.
Postdoctoral Researcher in Department of Microengineering, EPFL, Switzerland
− Developed and fabricated organ-on-chip for simulation of human gastrointestinal tract to investigate the beneficial effect of dairy food on human health.
− Assisted in the development of self-assembled microlens arrays to improve the sensitivity of surface-based immunoassays by enhancing fluorescence emission signal.
Research Assistant in Laboratory of Microsystems, EPFL, Switzerland
− Led the research and development of automated immunoassay platforms for point-of-care diagnostics.
− Developed a new low-cost strategy for rapid fabrication of custom protein microarrays; successfully performed fluorescent-based multi-biomarker detection tests on the fabricated microarrays for simultaneous monitoring of several diseases.
− Initiated the exploration of a new and simple method for rapid quantification of cancer protein biomarkers in blood serum down to extremely low concentration levels using magnetic bead surface coverage assays.
− Designed, modeled and fabricated microfluidic chips containing valves and chaotic mixers for low-cost, robust and portable bioanalysis; developed an experimental setup to automatically control fluidic manipulations using Labview program.
− Assisted in the development of DNA biosensor composed of interdigitated microelectrodes for food pathogen detection.
Research Engineer in Nanoelectronic Devices Laboratory, EPFL, Switzerland
− Designed, fabricated and characterized MEMS resonators integrated with field effect transistors for timing applications.
Honors and Prizes
Has an article selected among top 10% of Lab on a Chip articles
Nominated to Ville de Lausanne Award, Research Commission of EPFL, Lausanne, Switzerland
IEEE Special Prize in Competition of Senior Design projects, IEEE-METU, Ankara, Turkey
Skills and Expertise
Soft-lithography, photolithography, wet and dry etching, thin films, sputtering, evaporation, chemical vapor deposition (CVD), chemical mechanical polishing (CMP), dicing, scanning electron microscopy (SEM) and other methodology tools; gained 8-year of cleanroom experience.
MEMS, microfluidics, micro- and nanotechnology, biosensors, lab-on-a-chip, telemedicine, immunoassays, cell-based assays, automated fluidic manipulations inside a chip, surface chemistry, fluorescent microscopy, lensless microscopy, superparamagnetic nanoparticles, cell culture, impedance spectroscopy, rapid prototyping, multilayer microfluidic device fabrication, ASIC, PCB, FPGA, finite element modeling, computer-aided design.