Hüseyin Cumhur Tekin, PhD

Hüseyin Cumhur Tekin, PhD

 

İzmir Yüksek Teknoloji Enstitüsü, Biyomühendislik Bölümü

Fen Fakültesi A Blok, Oda 204

Gülbahçe Mahallesi, Urla/İzmir

 

 

 

 

Education

 

2007- 2012

PhD in Microsystems and Microelectronics, Ecole Polytechnique Federale de Lausanne (EPFL), Switzerland

Specialized in biomedical microfluidic systems

Thesis tittle: “Automated analysis of rare biomarkers using a magnetic bead surface coverage assay coupled with chaotic mixing on a microfluidic chip”

 

2005- 2007

MSc in Electrical and Electronics Engineering, EPFL, Switzerland

Specialized in microelectronics and microfabrication

Thesis title: “Process optimization for resonators with lateral MOSET detection”

 

2000- 2005

BSc in Electrical and Electronics Engineering, Middle East Technical University (METU), Turkey

Specialized in computer and telecommunication fields

 

Professional Experience

 

2016-

Assistant Professor in Department of Bioengineering, Izmir Institute of Technology (IZTECH), Turkey

 

2015-

Founder and CEO of Saniber Software, Engineering, R&D and Healthcare Services Co., Turkey

 

2014- 2015

Postdoctoral Research Fellow in Canary Center at Stanford for Cancer Early Detection, Department of Radiology, School of Medicine, Stanford University, USA

 

− Developed and characterized novel magnetic levitation based technology for real-time interrogation of both prokaryotic and eukaryotic cell types; enabled single-cell density measurements within a few minutes using automated program; used this technology for identification of cells and monitoring of heterogeneous biological changes under various physiological conditions, such as antibiotic or cancer treatment.

 

− Fabricated microfluidic chips composed of polymer micropillar arrays to sort efficiently motile sperms to be used in assisted reproductive technologies.

 

− Assisted in the development of graphene-based biosensors for early-detection of cancer by quantifying microRNA circulating in a blood stream based on electrical impedance spectroscopy.

 

2013- 2014

Postdoctoral Research Fellow in Department of Bioengineering, Brigham and Women’s Hospital, Harvard- Massachusetts Institute of Technology (MIT) Division of Health Sciences and Technology, Harvard Medical School, USA

 

− Developed and optimized telemedicine platform for early detection of infections in dialysis patients by monitoring white blood cell counts in peritoneal dialysis effluents.

 

− Collaborated with Brazilian scientists from Fiocruz (Belo Horizonte), IBMP (Curitiba) and CERTI (Florianopolis) to detect schitosoma eggs from stool samples in rural fields of Brazil using a microfluidic chip coupled with a lensless imaging system.

 

2012- 2013

Postdoctoral Researcher in Department of Microengineering, EPFL, Switzerland

 

− Developed and fabricated organ-on-chip for simulation of human gastrointestinal tract to investigate the beneficial effect of dairy food on human health.

 

− Assisted in the development of self-assembled microlens arrays to improve the sensitivity of surface-based immunoassays by enhancing fluorescence emission signal.

 

2007- 2012

Research Assistant in Laboratory of Microsystems, EPFL, Switzerland

 

− Led the research and development of automated immunoassay platforms for point-of-care diagnostics.

 

− Developed a new low-cost strategy for rapid fabrication of custom protein microarrays; successfully performed fluorescent-based multi-biomarker detection tests on the fabricated microarrays for simultaneous monitoring of several diseases.

 

− Initiated the exploration of a new and simple method for rapid quantification of cancer protein biomarkers in blood serum down to extremely low concentration levels using magnetic bead surface coverage assays.

 

− Designed, modeled and fabricated microfluidic chips containing valves and chaotic mixers for low-cost, robust and portable bioanalysis; developed an experimental setup to automatically control fluidic manipulations using Labview program.

 

− Assisted in the development of DNA biosensor composed of interdigitated microelectrodes for food pathogen detection.

 

2007

Research Engineer in Nanoelectronic Devices Laboratory, EPFL, Switzerland

 

− Designed, fabricated and characterized MEMS resonators integrated with field effect transistors for timing applications.

 

Honors and Prizes

 

2013

Has an article selected among top 10% of Lab on a Chip articles

 

2012

Nominated to Ville de Lausanne Award, Research Commission of EPFL, Lausanne, Switzerland

 

2005

IEEE Special Prize in Competition of Senior Design projects, IEEE-METU, Ankara, Turkey

 

Skills and Expertise

 

Microfabrication:

Soft-lithography, photolithography, wet and dry etching, thin films, sputtering, evaporation, chemical vapor deposition (CVD), chemical mechanical polishing (CMP), dicing, scanning electron microscopy (SEM) and other methodology tools; gained 8-year of cleanroom experience.

 

Programs:

MATLAB, Labview, Solidworks, COMSOL, L-Edit, ISE TCAD, Cadence IC and Encounter, Quartus II, Altium, VHDL, VHDL-AMS, C, C++, Java, Javascript, PHP, MySQL.

 

Others:

MEMS, microfluidics, micro- and nanotechnology, biosensors, lab-on-a-chip, telemedicine, immunoassays, cell-based assays, automated fluidic manipulations inside a chip, surface chemistry, fluorescent microscopy, lensless microscopy, superparamagnetic nanoparticles, cell culture, impedance spectroscopy, rapid prototyping, multilayer microfluidic device fabrication, ASIC, PCB, FPGA, finite element modeling, computer-aided design.

 

 

 

 

 © 2017 by Hüseyin Cumhur Tekin