Hüseyin Cumhur Tekin, PhD

Hüseyin Cumhur Tekin, PhD

 

İzmir Yüksek Teknoloji Enstitüsü, Biyomühendislik Bölümü

Fen Fakültesi A Blok, Oda 204

Gülbahçe Mahallesi, Urla/İzmir

 

 

 

 

Education

 

2007- 2012

PhD in Microsystems and Microelectronics, Ecole Polytechnique Federale de Lausanne (EPFL), Switzerland

Specialized in biomedical microfluidic systems

Thesis tittle: “Automated analysis of rare biomarkers using a magnetic bead surface coverage assay coupled with chaotic mixing on a microfluidic chip”

 

2005- 2007

MSc in Electrical and Electronics Engineering, EPFL, Switzerland

Specialized in microelectronics and microfabrication

Thesis title: “Process optimization for resonators with lateral MOSET detection”

 

2000- 2005

BSc in Electrical and Electronics Engineering, Middle East Technical University (METU), Turkey

Specialized in computer and telecommunication fields

 

Professional Experience

 

2016-

Assistant Professor in Department of Bioengineering, Izmir Institute of Technology (IZTECH), Turkey

 

2015-

Founder and CEO of Saniber Software, Engineering, R&D and Healthcare Services Co., Turkey

 

2014- 2015

Postdoctoral Research Fellow in Canary Center at Stanford for Cancer Early Detection, Department of Radiology, School of Medicine, Stanford University, USA

 

− Developed and characterized novel magnetic levitation based technology for real-time interrogation of both prokaryotic and eukaryotic cell types; enabled single-cell density measurements within a few minutes using automated program; used this technology for identification of cells and monitoring of heterogeneous biological changes under various physiological conditions, such as antibiotic or cancer treatment.

 

− Fabricated microfluidic chips composed of polymer micropillar arrays to sort efficiently motile sperms to be used in assisted reproductive technologies.

 

− Assisted in the development of graphene-based biosensors for early-detection of cancer by quantifying microRNA circulating in a blood stream based on electrical impedance spectroscopy.

 

2013- 2014

Postdoctoral Research Fellow in Department of Bioengineering, Brigham and Women’s Hospital, Harvard- Massachusetts Institute of Technology (MIT) Division of Health Sciences and Technology, Harvard Medical School, USA

 

− Developed and optimized telemedicine platform for early detection of infections in dialysis patients by monitoring white blood cell counts in peritoneal dialysis effluents.

 

− Collaborated with Brazilian scientists from Fiocruz (Belo Horizonte), IBMP (Curitiba) and CERTI (Florianopolis) to detect schitosoma eggs from stool samples in rural fields of Brazil using a microfluidic chip coupled with a lensless imaging system.

 

2012- 2013

Postdoctoral Researcher in Department of Microengineering, EPFL, Switzerland

 

− Developed and fabricated organ-on-chip for simulation of human gastrointestinal tract to investigate the beneficial effect of dairy food on human health.

 

− Assisted in the development of self-assembled microlens arrays to improve the sensitivity of surface-based immunoassays by enhancing fluorescence emission signal.

 

2007- 2012

Research Assistant in Laboratory of Microsystems, EPFL, Switzerland

 

− Led the research and development of automated immunoassay platforms for point-of-care diagnostics.

 

− Developed a new low-cost strategy for rapid fabrication of custom protein microarrays; successfully performed fluorescent-based multi-biomarker detection tests on the fabricated microarrays for simultaneous monitoring of several diseases.

 

− Initiated the exploration of a new and simple method for rapid quantification of cancer protein biomarkers in blood serum down to extremely low concentration levels using magnetic bead surface coverage assays.

 

− Designed, modeled and fabricated microfluidic chips containing valves and chaotic mixers for low-cost, robust and portable bioanalysis; developed an experimental setup to automatically control fluidic manipulations using Labview program.

 

− Assisted in the development of DNA biosensor composed of interdigitated microelectrodes for food pathogen detection.

 

2007

Research Engineer in Nanoelectronic Devices Laboratory, EPFL, Switzerland

 

− Designed, fabricated and characterized MEMS resonators integrated with field effect transistors for timing applications.

 

Board Memberships

 

2016-

Board member of Eurasian Centre for Advanced Research of IZTECH, Turkey

Academic board member of Photonics Department of IZTECH, Turkey

 

Honors and Prizes

 

2013

Has an article selected among top 10% of Lab on a Chip articles

 

2012

Nominated to Ville de Lausanne Award, Research Commission of EPFL, Lausanne, Switzerland

 

2005

IEEE Special Prize in Competition of Senior Design projects, IEEE-METU, Ankara, Turkey

 

Skills and Expertise

 

Microfabrication:

Soft-lithography, photolithography, wet and dry etching, thin films, sputtering, evaporation, chemical vapor deposition (CVD), chemical mechanical polishing (CMP), dicing, scanning electron microscopy (SEM) and other methodology tools; gained 8-year of cleanroom experience.

 

Programs:

MATLAB, Labview, Solidworks, COMSOL, L-Edit, ISE TCAD, Cadence IC and Encounter, Quartus II, Altium, VHDL, VHDL-AMS, C, C++, Java, Javascript, PHP, MySQL.

 

Others:

MEMS, microfluidics, micro- and nanotechnology, biosensors, lab-on-a-chip, telemedicine, immunoassays, cell-based assays, automated fluidic manipulations inside a chip, surface chemistry, fluorescent microscopy, lensless microscopy, superparamagnetic nanoparticles, cell culture, impedance spectroscopy, rapid prototyping, multilayer microfluidic device fabrication, ASIC, PCB, FPGA, finite element modeling, computer-aided design.

 

 

 

 

 © 2017 by Hüseyin Cumhur Tekin